姓名：颜军昊
邮箱：yyy306@126.com
个人简介/Personal resume
中组部“万人计划”科技创新领军人才
现任山东大学附属生殖医院副院长；山东省人类辅助生殖技术质量控制中心副主任；山东省生殖健康临床医学研究中心常务副主任
亚太生殖协会中国区代表（ASPIRE Country Representative for China）
研究领域/Research direction
本课题组研究---
主要研究课题：1. 复发性流产 2. 胚胎植入前遗传学检测
招生信息/Enrollment information
招生学科（一级和二级学科）：妇产科学
学科方向：生殖医学
荣誉奖励/Honors & Awards
作为主要参与者获得国家科技进步二等奖、山东省科技进步一等奖、山东省医学科技进步一等奖等奖项
代表性论文/Representative publications
1.Junhao Yan# , Yingying Qin# , Han Zhao# , Yun Sun#, Fei Gong #, Rong Li# , Xiaoxi Sun# , Xiufeng Ling #, Hong L#i, Cuifang Hao , Jichun Tan, Jing Yang , Yimin Zhu , Fenghua Liu, Dawei Chen , Daimin Wei , Juanjuan Lu , Tianxiang Ni , Wei Zhou , Keliang Wu , Yuan Gao, Yuhua Shi , Yao Lu , Ting Zhang, Wei Wu , Xiang Ma , Hailan Ma, Jing Fu, Junqiang Zhang, Qingxia Meng, Heping Zhang , Richard S Legro , Zi-Jiang Chen*. Live Birth with or without Preimplantation Genetic Testing for Aneuploidy. N Engl J Med. 2021 Nov 25;385(22):2047-2058
2.Yan Y, Zhang Q, Yang L, Zhou W, Ni T, Yan J*. Pregnancy and neonatal outcomes after long-term vitrification of blastocysts among 6,900 patients after their last live birth. Fertil Steril. 2022 Nov 28:S0015-0282(22)01966-5.
3.Wang J, Zhou W, Song Z, Ni T, Zhang Q, Chen ZJ, Yan J*. Does the risk of embryo abnormality increase in PCOS women? A secondary analysis of a multi-center randomized controlled trial. J Clin Endocrinol Metab. 2022 Dec 21:dgac726.
4.Sun F, Cheng L, Guo L, Su S, Li Y, Yan J*. Activin A promotes human trophoblast invasion by upregulating integrin β3 via ALK4-SMAD4 signaling. Placenta. 2022 Nov;129:62-69.
5.Lan X, Guo L, Zhu S, Cao Y, Niu Y, Han S, Li Z, Li Y, Yan J*. First-Trimester Serum Cytokine Profile in Pregnancies Conceived After Assisted Reproductive Technology (ART) With Subsequent Pregnancy-Induced Hypertension. Front Immunol. 2022 Jul 1;13:930582.
6.Shuo Li#, Shuiying Ma, Jialin Zhao, Jingmei Hu Hongchang Li, Yueting Zhu, Wenjie Jiang, Linlin Cui*, Junhao Yan* and Zi-Jiang Chen Non-Assisted Hatching Trophectoderm Biopsy Does Not Increase The Risks of Most Adverse Maternal and Neonatal Outcome and May Be More Practical for Busy Clinics: Evidence From China. Front. Endocrinol., 17 February 2022
7.Ni T, Wu Q, Zhu Y, Jiang W, Zhang Q, Li Y, Yan J*, Chen ZJ.Comprehensive analysis of the associations between previous pregnancy failures and blastocyst aneuploidy as well as pregnancy outcomes after PGT-A. J Assist Reprod Genet. 2020 Mar;37(3):579-588.
8.Yuhan Shao#, Jing Li , Juanjuan Lu, Hongchang Li , Yueting Zhu, Wenjie Jiang , Junhao Yan*. Clinical outcomes of Preimplantation genetic testing (PGT) application in couples with chromosomal inversion, a study in the Chinese Han population. Reprod Biol Endocrinol. 2020 Aug 5;18(1):79. doi: 10.1186/s12958-020-00635-7.
9.Qian Zhang#, Tianxiang Ni# , Yujie Dang , Lingling Ding Jingjing Jiang, Jing Li, Mingdi Xia, Na Yu , Jinlong Ma, Junhao Yan* , Zi-Jiang Chen. MiR-148a-3p may contribute to flawed decidualization in recurrent implantation failure by modulating HOXC8. J Assist Reprod Genet. 2020 Oct;37(10):2535-2544. doi: 10.1007/s10815-020-01900-9. Epub 2020 Aug 8.
10.Li Y#, Yan J#, Chang HM, Chen ZJ, Leung PCK.Roles of TGF-β Superfamily Proteins in Extravillous Trophoblast Invasion.Trends Endocrinol Metab. 2021 Mar;32(3):170-189.
11.Tingting Zhou, Tianxiang Ni, Yan Li, Qian Zhang , Junhao Yan*, Zi-Jiang Chen. circFAM120A participates in repeated implantation failure by regulating decidualization via the miR-29/ABHD5 axis.FASEB J. 2021 Sep;35(9):e21872.
12.Tianxiang Ni# , Qian Zhang #, Yan Li , Caiyi Huang , Tingting Zhou, Junhao Yan *, Zi-Jiang Chen . CircSTK40 contributes to recurrent implantation failure via modulating the HSP90 /AKT/FOXO1 axis. Mol Ther Nucleic Acids 2021 Dec 3;26:208-221.
13.Wu Q, Li H, Zhu Y, Jiang W, Lu J, Wei D, Yan J*, Chen ZJ.Dosage of exogenous gonadotropins is not associated with blastocyst aneuploidy or live-birth rates in PGS cycles in Chinese women. Hum Reprod. 2018 Oct 1;33(10):1875-1882. Zhang L#, Wei D, Zhu Y, Jiang W, Xia M, Li J, Yan J*, Chen ZJ. Interaction of acrocentric chromosome involved in translocation and sex of the carrier influences the proportion of alternate segregation in autosomal reciprocal translocations.Hum Reprod. 2019 Feb 1;34(2):380-387.
14.Zirui Dong#, Junhao Yan#, Fengping Xu#, Jianying Yuan#, Hui Jiang#,Huilin Wang, Haixiao Chen, Lei Zhang, Lingfei Ye, Jinjin Xu, Yuhua Shi,Zhenjun Yang,Ye Cao, Lingyun Chen, Qiaoling Li, Xia Zhao, Jiguang Li, Ao Chen,Wenwei Zhang,Hoi Gin Wong,Yingying Qin,Han Zhao, Yuan Chen,Pei Li,Tao Ma,Wen-Jing Wang,Yvonne K. Kwok,Yuan Jiang,Amber N. Pursley, Jacqueline P.W. Chung,Yan Hong,Karsten Kristiansen, Huanming Yang, Raul E. Pin˜a-Aguilar,Tak Yeung Leung, Sau Wai Cheung, Cynthia C. Morton,Kwong Wai Choy*&, and Zi-Jiang Chen*. Genome Sequencing Explores Complexityof Chromosomal Abnormalities in Recurrent Miscarriage. Am J Hum Genet. 2019 Dec 5;105(6):1102-1111.
15.Xu C, Zhang FF, Li HC, Wang MM, Zhu YT, Jiang WJ, Wang Y, Zhang HB, Tang R, Ma G, Yan JH*. Outcomes of Preimplantation Genetic Diagnosis Cycles by Fluorescent In situ Hybridization of Infertile Males with Nonmosaic 47,XYY Syndrome. Chin Med J 2018;131:1808-12.
